Researching adult parvo virus

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Нетёсов Сергей Викторович

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Нетёсов Сергей Викторович | Novosibirsk state university

Monoblasts can be distinguished by having a roughly circular nucleus, delicate lacy chromatin, and abundant, often basophilic cytoplasm. These cells may also have pseudopods. By contrast, promonocytes have a more convoluted nucleus, and their cytoplasm may contain metachromatic granules. Monoblasts may be positive for CD M5 is associated with characteristic chromosomal abnormalities, often involving Chromosome 11 at 11q23 or t 9;11 affecting the MLL locus, however the MLL translocation is also found in other AML subtypes. The t 8;16 translocation in MLL is associated with hemophagocytosis. Secondary leukaemia, which may include AML-M5, has been associated with exposure to epipodophyllotoxins, such as etoposide.
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