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Objectives: To assess current knowledge of sexually transmitted viral hepatitis in relation to epidemiology, clinical presentation, management, and diagnosis with particular reference to resource-poor settings. Method: A search of published literature identified through Medline from to October , the Cochrane Library, and reference lists taken from each article obtained. Conclusions: In heterosexual relationships, hepatitis B is readily transmitted sexually and hepatitis C and D less so, with no evidence for sexual transmission of hepatitis A. In resource-poor countries sexual transmission is generally only a significant route of transmission for hepatitis B. National Center for Biotechnology Information , U.